Evidence suggests that CBD alone or in combination with THC can suppress chronic neuropathic pain and that CBD may have a protective effect after nerve injury. Pain relief is the primary benefit of THC as a treatment for neuropathy. Studies show that people with neuropathic pain experience pain reduction while undergoing THC therapy. Pain intensity decreases with prolonged use.
A growing number of states allow medical marijuana for peripheral neuropathy and neuropathic pain. If you have problems with the constant pain, numbness, and weakness associated with this common condition, cannabis can help provide the relief you're looking for. A study conducted at UC Davis Medical Center examined the effects of cannabis use for pain management in 38 patients with complex regional pain syndrome, spinal cord injury, peripheral neuropathy, and sensory neuropathy. For example, one study found that 25 mg of cannabis with 9.4% THC is effective for neuropathic pain when smoked three times a day for five days.
A cost-effectiveness model of complementary smoked cannabis in the treatment of chronic neuropathic pain. Unbalanced synaptic communication in the dorsal horn of the spinal cord is one of the main causes of consolidation of chronic neuropathic pain. With the use of the aerosol, pain intensity decreased by at least half in 67.5% of patients, having a better effect in neuropathic and mixed pain patients. Cannabidiol (CBD) has been identified for its potential benefits for neuropathy, as well as its potential for general inflammation and pain relief.
The fact that SCs are involved in the pathophysiological state of pain makes this system a valid target for the treatment of chronic neuropathic pain. Researchers at the Center for Pain Medicine at the University of California, San Diego, examined the body of existing research on the use of cannabis for neuropathy. Commonly, such patients take conventional analgesics for their nociceptive pain, as well as unconventional analgesics, antidepressants and antiepileptics for the neuropathic element of their pain. The authors should be commended for addressing the question of whether cannabis helps with neuropathic pain, especially since regulatory obstacles to its trial must have been a nightmare.
Multiple randomized controlled trials found that cannabis is as effective as common drugs in treating neuropathic pain. Although these studies consisted of small sample sizes and were conducted over short periods of time, the results were consistent enough to suggest that cannabis may be safe and effective in treating neuropathic pain. They concluded that medical marijuana may be effective as an alternative or additional pain treatment for peripheral neuropathy based on several small clinical studies. There is no cure for peripheral neuropathy, but pain can be reduced and controlled with certain medications.
In the clinical review mentioned above, researchers found that low-dose cannabis vaporization and oral mucosal administration are particularly safe and effective for neuropathic pain.
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